Mood disorders, such as depression and bipolar disorder, are physical conditions that affect the brain. Most mood disorders have in common the occurrence of major depressive episodes—times when individuals experience prolonged sadness or hopelessness, irritability, inability to concentrate or take pleasure in daily life, and other potentially debilitating symptoms, which may include recurring thoughts of death or suicide. Bipolar disorder is characterized by extreme changes in mood, thought, energy, and behavior...
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